Main clinical trials published 2021-2026
Cosmetic Results and Side Effects of Accelerated Partial-Breast Irradiation Versus Whole-Breast Irradiation for Low-Risk Invasive Carcinoma of the Breast: The Randomized Phase III IRMA Trial
Meduri B, Baldissera A, Iotti C, Scheijmans LJEE, Stam MR, Parisi S, Boersma LJ, Ammendolia I, Koiter E, Valli M, Scandolaro L, Busz D, Stenfert Kroese MC, Ciabatti S, Giacobazzi P, Ruggieri MP, Engelen A, Munafò T, Westenberg AH, Verhoeven K, Vicini R, D’Amico R, Lohr F, Bertoni F, Poortmans P, Frezza GP.
J Clin Oncol. 2023 Apr 20;41(12):2201-2210. doi: 10.1200/JCO.22.01485. Epub 2023 Jan 9. PMID: 36623246.
Nine-week Versus One-year Trastuzumab For Early Human Epidermal Growth Factor Receptor 2–positive Breast Cancer: 10-year Update Of The Shorther Phase Iii Randomized Trial
PierFranco Conte, Giancarlo Bisagni, Federico Piacentini, Samanta Sarti, Santino Minichillo, Elisa Anselmi, Michele Aieta, Vittorio Gebbia, Alessio Schirone, Antonino Musolino, Ornella Garrone, Alessandra Beano, Anita Rimanti, Francesco Giotta, Anna Turletti, Federica Miglietta, Maria Vittoria Dieci, Roberto Vicini, Sara Balduzzi, Robert D’Amico, Valentina Guarneri
Journal of Clinical Oncology 2023 41:32, 4976-4981
Randomized, Double-blind, Placebo-controlled Trial Of Rapamycin In Amyotrophic Lateral Sclerosis
Mandrioli J, D’Amico R, Zucchi E, De Biasi S, Banchelli F, Martinelli I, Simonini C, Lo Tartaro D, Vicini R, Fini N, Gianferrari G, Pinti M, Lunetta C, Gerardi F, Tarlarini C, Mazzini L, De Marchi F, Scognamiglio A, Sorarù G, Fortuna A, Lauria G, Bella ED, Caponnetto C, Meo G, Chio A, Calvo A, Cossarizza A.
Nat Commun. 2023 Aug 17;14(1):4970. doi: 10.1038/s41467-023-40734-8. PMID: 37591957; PMCID: PMC10435464.
Colchicine Treatment In Amyotrophic Lateral Sclerosis: Safety, Biological And Clinical Effects In A Randomized Clinical Trial
Gianferrari G, Cuoghi Costantini R, Crippa V, Carra S, Bonetto V, Pansarasa O, Cereda C, Zucchi E, Martinelli I, Simonini C, Vicini R, Fini N, Trojsi F, Passaniti C, Ticozzi N, Doretti A, Diamanti L, Fiamingo G, Conte A, Dalla Bella E, D’Errico E, Scarian E, Pasetto L, Antoniani F, Galli V, Casarotto E; Co-ALS Investigators Group; D’Amico R, Poletti A, Mandrioli
J. Brain Commun. 2024 Sep 5;6(5):fcae304. doi: 10.1093/braincomms/fcae304. PMID: 39291166; PMCID: PMC11406549.
Immune Effects Of Faecal Microbiota Transplantation In Amyotrophic Lateral Sclerosis: A Pilot Multicentre, Randomised, Masked, Sham-controlled, Proof-of Concept Trial
Elisabetta Zucchi, Elena Niccolai, Flavio De Maio, Riccardo Cuoghi Costantini, Gianluca Quaranta, Alessandra Guarnaccia, Stefano Bibbò, Ilaria Martinelli, Giulia Gianferrari, Cecilia Simonini, Giulia Nannini, Matteo Lulli, Simone Baldi, Gianluca Bartolucci, Roberto Vicini, Margherita Capasso, Giulia Bisogni, Amelia Conte, Paola Brunori, Giovanni Cammarota, Sabrina Paganoni, Roberto D’Amico, Amedeo Amedei, Luca Masucci, and Jessica Mandrioli, on behalf of the FETR-ALS Study Group.
The lancet Vol 133 November, 2026. https://doi.org/10.1016/j.ebiom.2026.106509